59. JENNIFER-ANN SCRUBB
Information acquired: 2025
JENNIFER-ANN SCRUBB is an academic who published a paper in 1994 entitled Protein composition of erythrocytes and skeletal muscle cells in malignant hyperthermia. JENNIFER-ANN SCRUBB published this work as part of a team: Scrubb, Jennifer Ann. Here is a description of this work: The,,purposes of this study were to, 1. Compare the protein composition of erythrocyte (RBC) ghosts from whole blood (fresh and frozen) and frozen ghosts extracted from Yorkshire (Y) and Pietrain (P) swine and 2. Determine the amount of calpain-mediated degradation of beta-spectrin from Yorkshire and Pietrain ghosts. In addition protein composition of purified myofibrils from Yorkshire, Heterozygote (H) and Pietrain skeletal muscle was compared. Longissimus Dorsi (LD) muscle and whole venous blood was obtained from Yorkshire (N=10), Pietrain (N=10), and Heterozygote (N=8) fasted swine (50-70 kg) housed at the University of Guelph (Guelph, Ontario) experimental farm. RBCs were hemolysed in a hypotonic buffer (imidazole, EDTA, PMSF) and ghosts were obtained by ultracentrifugation and stored at -70°C. Myofibrils were prepared by diff.