1. VIVAN PROMPRADITH
Information acquired: 2025
VIVAN PROMPRADITH is an academic who published a paper in 2015 entitled Mechanism of antiplatelet aggregation of angelica dahurica extract in human platelets. VIVAN PROMPRADITH published this work as part of a team: Prompradith, Vivan. Here is a description of this work: Ang,,lica dahurica extract (ADE) has been shown to exhibit antiplatelet aggregation properties, which promise to be used as a therapeutic agent for circulatory disorder. The aim of the present study was to investigate the mechanism of ADE in antiplatelet aggregation in human platelets. The effect of ADE on human platelet aggregation induced by adenosine diphosphate (ADP, 40 µM) and collagen (20 µg/ml) were explored in vitro, and the potential mechanism such activity were investigated using western blot analysis. The result showed that ADE at the concentration of 0. 1, 0. 25, 0. 5 and 1 mg/ml significantly inhibited ADP-induced platelet aggregation by 38. 2±13. 7% (p<,0. 05), 50. 2±11. 6% (p=0. 01), 73. 4±8. 5% (p<,0. 001) and 79. 8±7. 4% (p<,0. 001), respectively when compare to vehicle control. ADE at the concentration of 0. 5 and 1 mg/m.