42. ANN-EN-JU LIN
Information acquired: 2025
ANN-EN-JU LIN is an academic who published a paper in 2008 entitled Atypical roles for campylobacter jejuni AA-ABC transporter components PAQP and PAQQ in bacterial str. ANN-EN-JU LIN published this work as part of a team: Lin, Ann En-Ju. Here is a description of this work: Cam,,ylobacter jejuni is a human pathogen that causes severe diarrhea! Disease. However, our understanding of C. Jejuni virulence mechanisms and survival during disease and transmission remains limited. Amino acid ATP Binding Cassette (AA-ABC) transporters in C. Jejuni have been proposed as being important for bacterial physiology and pathogenesis. We have investigated a novel AA-ABC transporter system, encoded by cj0467-9, by generating targeted deletions of cj0467 (membrane transport component) and cj0469 (ATPase component) in C. Jejuni 81-176. Analyses described herein have led us to designate these genes paqP and paqQ, respectively [pathogenesis-ssociated glutamine (q) ABC transporter permease () and ATPase (Q) ]. We found that loss of either component resulted in amino acid uptake defects, most notably diminished glutamine.