11. ROMAN DOMSZY ♂
Information acquired: 2025
ROMAN DOMSZY is an academic who published a paper in 2019 entitled Effect of a Cationic Surfactant on Microemulsion Globules and Drug Release from Hydrogel Contact Len. ROMAN DOMSZY published this work as part of a team: Torres-Luna, Cesar. Here is a description of this work: The,,present study evaluates the in vitro release of diclofenac sodium (DFNa) from contact lenses based on poly-2-hydroxyethyl methacrylate (pHEMA) hydrogels containing an embedded microemulsion to extend release duration. The oil (ethyl butyrate) -in-water microemulsion systems are prepared with two non-ionic surfactants, Brij 97 or Tween 80, together with a long-alkyl chain cationic surfactant, cetalkonium chloride (CKC). Without CKC, Brij 97 or Tween 80-based microemulsions showed average droplet sizes of 12 nm and 18 nm, respectively. The addition of CKC decreased the average droplet sizes to 2â€"5 nm for both non-ionic surfactants. Such significant reduction in the average droplet size corresponds to an increase in the DFNa release duration as revealed by the in vitro experiments. Contact lens characterization showed that important properti.