49. PIERPAOLO CONI
Information acquired: 2025
PIERPAOLO CONI is an academic who published a paper in 2011 entitled Association between the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism an. PIERPAOLO CONI published this work as part of a team: Demurtas, Paolo. Here is a description of this work: Pterygium is a common ocular surface disorder characterized by proliferation, inflammatory infiltrates, fibrosis, angiogenesis and extracellular matrix breakdown. Epidemiological studies indicate exposure chronic to UVB light as the most important risk factor for the development of pterygium. The Angiotensin Converting Enzyme (ACE) is the major component of the Renin-angiotensin system (RAS). It converts the inactive decapeptide Angiotensin I (Ang I) to the active octapeptide Angiotensin II (Ang II). Ang II is the most potent vasoconstrictor and stimulant of the aldosterone release. Recent discoveries have demonstrated that Ang II is also involved in cell proliferation, apoptosis, angiogenesis and tissue fibrosis. Moreover, it acts as growth factor and participates in inflammatory responses. The gene encoding ACE is.