4. PIER-GIULIO CONALDI
Information acquired: 2025
PIER-GIULIO CONALDI is an academic who published a paper in 2015 entitled Wha,,ton's jelly mesenchymal stromal cells immunomodulatory molecules: their journey from umbilical. PIER-GIULIO CONALDI published this work as part of a team: Anzalone, Rita. Here is a description of this work: Wha,,ton's jelly mesenchymal stromal cells (WJ-MSCs) have a unique ability to cross lineage borders. Their immunomodulatory and anti-inflammatory features, further render these cells promising for regenerative medicine applications. Few data are present in literature on the expression of immunomodulatory molecules in umbilical cord (UC) tissue and their maintenance in paired cultured WJ-MSCs, an important aspect in cellular therapy applications. In addition, few data exist on the maintenance of expression of immunomodulatory molecules in mature cell types differentiated from MSCs. Therefore we investigated, in vivo (in UC at full term) and in vitro (in either undifferentiated or differentiated WJ-MSCs), the expression of different markers and their maintenance alongside cell culture, ex vivo expansion and differentiat.