6. ELISA CAPILUPPI
Information acquired: 2025
ELISA CAPILUPPI is an academic who published a paper in 2015 entitled MAL,,TTIA DI HUNTINGTON AD ESORDIO TARDIVO:ENTITA� CLINICA DISTINTA?. ELISA CAPILUPPI published this work as part of a team: CAPILUPPI, ELISA. Here is a description of this work: Introduction: Huntington?s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG expansion in the HTT gene and characterized by motor symptoms (chorea), cognitive impairment and psychiatric manifestations. It usually has onset in adult life between the ages of 30 and 50, and leads to death within 17-20 years. When onset falls outside the usual age spectrum, diagnosis may be more challenging and prognosis may be different. The term ?late-onset HD?, encompassed in earlier papers all cases with symptoms onset above age 60. There are few reports that have focused specifically on late-onset HD. They have concluded that motor problems are predominant, cognitive decline is mild, psychiatric manifestations are rare, and that disease progression is slower. However, these were purely observational studies in which no comparisons were.