3. ALESSANDRO CALAMUNERI
Information acquired: 2025
ALESSANDRO CALAMUNERI is an academic who published a paper in 2017 entitled Top,,-pathological re-wiring in brain structural connectomes of de novo Parkinson's Disease patient. ALESSANDRO CALAMUNERI published this work as part of a team: Bramanti, Placido. Here is a description of this work: Alt,,ough several studies in the last decades have challenged our understanding of Parkinson's Disease (PD) pathophysiology, an important gap at a network and system level still remains to be filled in order to understand the fundamental changes in high-order motor and non-motor circuits underlying PD symptoms. The wide spectrum of both motor and non-motor symptoms suggests that Parkinson's Disease may reflect extended alterations of the global brain network, thus justifying the onset of this heterogeneous symptomatology. Such hypothesis would be suitable with the idea of an â€oeassociationist†brain, which goes beyond the classic cortical â€oelocalizationist†theory. According to the former, the brain might consist of several, segregated and parallel distributed networks around critical and participating cortical epicenters. T.