16. DRAGOSLAV BASIC
Information acquired: 2025
DRAGOSLAV BASIC is an academic who published a paper in 2015 entitled The,,role of intrinsic pathway in apoptosis activation and progression in Peyronie's disease. DRAGOSLAV BASIC published this work as part of a team: Loreto, Carla. Here is a description of this work: Pey,,onie's disease (PD) is a connective tissue disorder where formation of fibrous plaques in tunica albuginea (TA) and erectile tissue can result in penile deformity, pain, and erectile dysfunction. Fibrosis, its major pathological manifestation, arises from fibroblast proliferation and accumulation of extracellular matrix, PD progresses with formation of plaques or even ectopic calcification having the appearance of scar tissue, which prevent TA expansion during erections. The mechanisms underpinning PD are unclear, and relatively little is known about the disease itself. To date corrective surgery is the sole effective treatment. A greater understanding of PD pathophysiology at the molecular level has the potential to help develop novel medical therapeutic approaches. The aim of this study was to investigate the activatio.