1. HENRY ASHPITEL ♂
Information acquired: 2025
HENRY ASHPITEL is an academic who published a paper in 2020 entitled The effects of endothermal ablation devices on the vein wall : a histological and immunohistochemica. HENRY ASHPITEL published this work as part of a team: Ashpitel, Henry. Here is a description of this work: Var,,cose veins, often thought as a purely cosmetic issue, are a common symptom resulting from chronic venous insufficiency (CVI). CVI can result in serious fasciocutaneous and haematological complications. In 2013, NICE recommended that the treatment of varicose veins should preferably be carried out by endothermal ablation (ETA). The mechanism of action of ETA is still not fully understood. In 2004 it was suggested that successful treatment must involve transmural vein wall death (TMVD) in the target vein. Through the development of a novel in-vitro¬ model, using ex-vivo veins, the work carried out in this thesis has indicated that TMVD is reliant on a combination of thermal necrosis, followed by the upregulation of apoptosis. The novel model has been used to compare four different ETA techniques, endovenous laser ablation (EVLA) usi.