2. CHIARA ADEMBRI
Information acquired: 2025
CHIARA ADEMBRI is an academic who published a paper in 2013 entitled Sepsis worsens the neurological outcome of traumatic brain injury: role of sialic acids related to g. CHIARA ADEMBRI published this work as part of a team: Pacini, Alessandra. Here is a description of this work: Mic,,oglial cells are the brain resident macrophages that, in response to brain injury, changes its phenotype from ramified to ‘‘activated'' ameboid, increase motility to the site of damage and secrete soluble factors that modulate surrounding environment [1]. Astrocytes are the predominant glial cell type in the CNS that play a central role in forming the inhibitory glial scar contributing to neuroprotection and repair. As well as microglia they change morphology after injury, undergoing to hypertrophy and forming a dense network bording the lesion site [2]. Both, in healthy and damaged CNS, these processes are controlled by intracellular interactions of glial cells with several components of the brain microenvironment [3]. Between them sialic acids are one of the most important glycans expressed at the cell.